Yes, but with tweaks. You disable driver signature enforcement (Method 3) during installation. After the first successful install, the driver will continue to work after normal reboots.
macOS dropped support for ZTE 3G modems after High Sierra (10.13). However, users with older Macs can still succeed. zte mf180 driver install
If your computer refuses to recognize the modem, or if you see "Device not recognized" or "Hardware ID missing," you are not alone. The ZTE MF180 functions as a "virtual CD-ROM" initially, and installing the correct drivers requires a specific workflow. Mastering the ZTE MF180 Driver Install: A Complete
: Includes a microSD slot for external storage, effectively turning the modem into a USB flash drive. Driver Installation Guide Control Panel → Network and Sharing Center →
*99# or *99***1#internet (or blank)internet (or blank): Connect the modem to your Mac. A new CD-ROM icon should automatically appear on your desktop.